Control PID de temperatura-humedad-CO2 en una cámara para técnicas de bioimpresión

Abstract

The evolution of additive manufacturing techniques applied to medicine, in particular to tissue engineering, is known as bio-printing. In this new field of research, three-dimensional structures are recreated using hydrogels and cells. The bioprinting process is complex and highly dependent on both, internal factors (materials or cells) and external process conditions (temperature, humidity, etc...). It is necessary to control these factors to obtain a specific geometry with good cell survival. Therefore, the machinery used in bioprinting is complex and not very affordable. However, many working groups are developing low-cost, open-source bioprinters with specific functionalities for subsequent processes or cell lines. In this sense, our research group is developing a low-cost bioprinter with a temperature, humidity and CO2 PID controlled atmosphere system. Therefore, the objective of this work is the design and control of this bioprinting chamber. The control has been carried out with simulation tests using Simulink in order to ensure the proper operation of all its components.